Varicella Zoster & Herpes Zoster

Varicella Zoster
Chicken Pox: common illness that causes itchy red macules, papules, vesicles, pustles then scabs all over the body;different stages at the same time. Most common in children, but most people will contract chickenpox at some point in their lives if they have not received the chickenpox vaccine.

Herpes Zoster
viral disease also known as shingles. Had to already have chicken pox (virus stays dormant in the dorsal root ganglion)Highly painful lesions found in a dermotomal distribution. Usually follows the body along certain nerve pathways. Can spread the virus until blisters dry and crust over. the spread of the shingles virus will cause chicken pox in those who havenot had it nor been vaccinated.

chickenpox pathology & symptoms
fever of 100.4F
feeling sick, tired and sluggish
little or no appetite
headache and sore throat
red itchy body rash becomes fluid filled vesicles
vesicles open & yield infectious virus laden fluid
most contagious 2-3 days prior to rash until all blisters have dried and crusted over. the fluid in the pimple-like pustules release the highly infectious droplets into the air and any nearby food and water/an hour of exposure is all you need.

shingles pathology
vescicles occur along skin in areas supplied by certain sensory nerve
occurs unilaterally most prominent on head – neck – upper torso
occurs primarily in older adults and immunocompromised individuals
more likely to develop this condition if:
you are older than 60
you had chickenpox before age 1
you have a weakened immune system from medications or chronic disease
also triggered by chronic stress

shingles symptoms
abdominal pain
chills & fever
difficulty moving some facial muscles
drooping eyelid
loss of eye motion
swollen glands
general malaise

chickenpox treatment
Symptomatic, Antipyretic, Antihistamines, Nails short – prevent scratching, No Aspirin, Zovirax – topically, systemically, or parenterally. Soothing oatmeal baths. Calamine lotion topically. Fluids and chicken soup.

shingles treatment
2006 FDA approved a zoster vaccine
Only for people 60 years or older
Treatment for symptom relief only
Some patients retain pain after recovery
called “postherpetic neuralgia”

persons at risk
you are at risk for chickenpox if:
you have not been vaccinated and you…
live with someone who has chickenpox
are indoors for more than an hour with a patient
share a hospital room with infected patient
have an impaired immune system

Varicella Zoster Chicken pox occurs most often in children 13: 2 doses, 4-8 weeks apart Unvaccinated: give 3-5 days after exposure for PEP (reduces severity) Risks with Varivax Incomplete immunity (70-98%). For young girls: risk of acquiring chicken pox later …

Caused by varicella-zoster (same as chicken pox) Characteristics Linear vesicular lesions that do not cross the midline. Pain is described as burning, throbbing, or stabbing…some pts have intense itch WE WILL WRITE A CUSTOM ESSAY SAMPLE ON ANY TOPIC SPECIFICALLY …

What do herpesviruses look like? • 180-200 nm in diameter • Large genome:100-250 kbp • Enveloped viruses are labile 不稳定的 in the environment: infectious virions survive up to 2 hours on skin, up to 4 hours on plastic surfaces What …

A common viral infection that tends to recur repeatedly. Herpes Simplex Virus (HSV) Infection That cause by type 1 virus (HSV-1), which occurs above the waist and causes a fever blister or cold sore. That caused by type 2 virus …

To what family does VZV belong? Herpesviridae What species is VZV? *Human herpesvirus 3* WE WILL WRITE A CUSTOM ESSAY SAMPLE ON ANY TOPIC SPECIFICALLY FOR YOU FOR ONLY $13.90/PAGE Write my sample What type of genome does VZV have? …

Herpes Zoster dt Acute-first stage sx Burning stabbing pain on affected skin area, small bead rash, slight fever, fatigue, poor appetite, decreased sleep, weight loss. With continued development, small vesicles quickly develop into small groups of blisters arranged in bands. …

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