pharmacology made easy

Ace inhibitors
These tend to end in “pril”
EXAMPLE: benzapril

Ace inhibitors
Either used for blood pressure of Chf, can lead to renal profusion

Contradictions for ace inhibitors
Common adverse drug reactions include: hypotension, cough, hyperkalemia, headache, dizziness, fatigue, nausea, and renal impairment. [12] Some evidence also suggests ACE inhibitors might increase inflammation-related pain, perhaps mediated by the buildup of bradykinin that accompanies ACE inhibition. Rash and taste disturbances, infrequent with most ACE inhibitors, are more prevalent in captopril and is attributed to its sulfhydryl moiety. This has led to decreased use of captopril in clinical setting, although it is still used in scintigraphy of the kidney. Renal impairment is a significant adverse effect of all ACE inhibitors, but the reason is still unknown.

An ACE inhibitor (or angiotensin-converting-enzyme inhibitor) is a medication pharmaceutical drug used primarily for the treatment of high blood pressure (hypertension) and weak heart muscle. (congestive heart failure). This group of drugs causes dilation of blood vessels which results in lower blood pressure. In treating heart disease ACE inhibitors are usually used with other medications. A typical treatment plan will often include an ACE inhibitor, beta blocker, a long acting nitrate and a calcium channel blocker in combinations that are adjusted to the individual patient’s needs.
What is an ace inhibitor

molecular structure:

Sulfhydryl-containing agents Captopril (trade name Capoten), the first ACE inhibitor Zofenopril

Dicarboxylate-containing agents This is the largest group, including: Enalapril (Vasotec/Renitec) Ramipril (Altace/Prilace/Ramace/Ramiwin/Triatec/Tritace) Quinapril (Accupril) Perindopril (Coversyl/Aceon) Lisinopril (Listril/Lopril/Novatec/Prinivil/Zestril) Benazepril (Lotensin) Imidapril (Tanatril) Zofenopril (Zofecard) Trandolapril (Mavik/Odrik/Gopten)

Phosphonate-containing agents Fosinopril (Fositen/Monopril) is the only member of this group

Types of ace inhibitors

Acetylcholinesterase inhibitor
Used to treat Alzheimer’s dieseas

Donezipril (aricept) rivastigmine tarcine, galantamine
Drugs used to treat Alzheimer’s

-zosin (prazosin) *Alpha Blocker* Used for BPH and Hypertension -olol, -lol (metoprolol) *Beta Blocker* Cardioselective beta1 blocker WE WILL WRITE A CUSTOM ESSAY SAMPLE ON ANY TOPIC SPECIFICALLY FOR YOU FOR ONLY $13.90/PAGE Write my sample -zepam, -zolam (diazepam, alprazolam) …

What ate four types of RAAS supressants that support the treatmrnt of hypertension? Ace inhibitors Arbs Aldosterone antagonists Direct renin inhibitors Ace inhibitors treat ? Hypertension Heart failure Disbetic nephropathy Left ventricular dysfunction following MI WE WILL WRITE A CUSTOM …

26/08/2013 Learning Objectives: After completing this chapter you should able to: •Name categories of cardiovascular drugs •Describe the therapeutics effects of drugs •Identify the side effects 2 26/08/2013 Heart & Blood Circulation 3 functional parts: • • • Cardiac muscle …

This antihypertensive suffix is? Pril What is the prototype for the ACE inhibitor? Captopril (capoten) WE WILL WRITE A CUSTOM ESSAY SAMPLE ON ANY TOPIC SPECIFICALLY FOR YOU FOR ONLY $13.90/PAGE Write my sample What is the action of an …

ACEi Angiotensin converting enzyme inhibitors (ACE inhibitors) drugs blocking the body’s production of angiotensin II, a hormone that circulates in the blood and has many effects on the cardiovascular system; main role: constrict blood vessels – CILAZAPRIL Alpha-blocker Any drug …

A health care professional is caring for a patient who is about to begin taking verapamil (Calan) to treat atrial fibrillation. The health care professional should tell the patient to avoid grapefruit juice while taking verapamil because it can cause …

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