Pharmacology Lungs Partition Coefficient

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Sevoflurane MAC %
2

Isoflurane MAC %
1.15

Nitrous Oxide MAC %
105

Desflurane MAC %
5.8

Sevoflurane Blood Gas/ Partition Coefficient
0.6

Isoflurane Blood Gas/ Partition Coefficient
1.4

Nitrous Oxide Blood Gas/ Partition Coefficient
0.47

Desflurane Blood Gas/ Partition Coefficient
0.42

Sevoflurane Oil/Gas Coefficient
50

Isoflurane Oil/Gas Coefficient
99

Nitrous Oxide Oil/Gas Coefficient
1.4

Desflurane Oil/Gas Coefficient
18.7

Definition of MAC
minimum alveolar concentration required to achieve surgical anesthesia in 50% of patients exposed to a noxious stimulus

Concentration of gas equals
Concentration in brain

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