Pharmacology – Haldol

Class
Anti-psychotic and Neuroleptic

Description
Major tranquilizer

Mechanism of Action
Blocks dopamine receptors in the brain, altering mood and behavior.

Major tranquilizer of the butyrophenone class that has proved effective in the management of acute psychotic episodes.

has pharmacological properties similar to those of the phenothiazine class of drugs (Thorazine)

Has weak anticholinergic properties

Pharmacokinetics
Onset: 30-45 mins
Peak: 10-20 mins
Duration: variable
Half Life: 3-35 hours

Indications
Acute psychotic episodes.

Contraindications
Central nervous system depression / coma
Hypersensitivity
Pregnancy

Precautions
May impair mental and physical abilities
Use with caution in patients taking anticoagulants
Diphenhydramine / benadryl should be available

Few incidents of reported prolonged QT intervals that did produce some cases of torsades de pointes, much higher doses than used in prehospital care.

Side Effects
Extraphyramidal reaction or symptoms (EPR or EPS) especially in children.
Hypotension
Nausea / Vomiting
Blurred vision

Interactions
Anti-hypertensive medications may increase the likelihood of a patient developing hypotension.

use with caution in patients taking lithium, because irreversible brain damage has been reported.

Dosage
2 to 5 mg IM

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Drug classification – conventional antipsychotic Dose range – PO: 2-20 mg/daily in divided doses – IM: 2-5 mg. q1-8 hr, not to exceed 100 mg/day Depot injection: – Haloperidol Decanoate – 50 to 100 mg q4weeks WE WILL WRITE A …

ADENOSINE indications for use *First drug for most forms of stable narrow complex SVT. *Effective in terminating those due to reentry involving AV node or sinus node. AMIODARONE indications for use *VF/pulseless VT unresponsive to shock delivery, CPR, and a …

Adenosine – Indications – First drug for most forms of stable narrow-complex SVT – Effective in terminating reentry involving AV node/sinus node – Narrow-complex reentry tachycardia while prepping for cardioversion – Wide-complex tachycardia, thought to be reentry SVT – Doesn’t …

Psychoses Schizophrenia is the primary reason for the administration of antipsychotic medications. Schizophrenia symptoms (+) symptoms- agitation, delusions, hallucinations, tangential speech patterns (-) symptoms – social withdrawal, lack of emotion, lack of energy, flattened affect, decreased motivation, decreased pleasure in …

Acetaminophen Class: Anti-pyretic Indications: Fever Contraindications: Liver failure; hypersensitivity; exceed max dose Side effects: Liver toxicity Adult Dose: 1 g q 6 hours; max 4 g in 24 hours Pediatric Dose: 15 mg/kg q 6 hours Special info: Tylenol Aspirin …

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