Pharmacology EXAM ONE

Adverse effects
General term for undesirable and potentially harmful drug effect

Agonist
Drug that binds to a receptor and activates a physiological response or drug action

Antagonist
Drug that binds to a receptor and interferes with other drugs or substances from producing a drug effect

Chemical name
Name that defines the chemical composition of a drug

Contraindications
Situations or conditions when a certain drug should not be administered

Controlled substances
Drug that has the potential for abuse and this is regulated by law

Dose
A measurement of the amount of drug that is administered

Drug
Chemical substance that produces a change in body function

Drug indications
Intended or indicated uses for any drug

ED50
Effective dose 50, or dose that will produce an effect that is half of the maximal response

Generic name
Nonproprietary name of a drug

LD50
Lethal dose 50, or dose that will kill 50 percent of the laboratory animals tested

Mechanism of action
Explanation of how a drug produces its effect

Non-prescription, OTC
Drug that can purchased without the services of a physician

Pharmacology
Study of drugs

Potency
Measure of the strength, or concentration, of a drug required to produce a specific effect

Prescription drug
Drug for which dispensing requires a written or phone order that can be issued by or under the direction of a licensed physician

Receptor
Specific cellular structure that a drug binds to and that produces a physiological effect

Side effect
Drug effect other than the therapeutic effect that is usually undesirable but not harmful

Site of action
Location of within the body where a drug exerts its therapeutic effect, often a specific drug receptor

Therapeutic effect
Desired drug effect to alleviate some condition or symptom of disease

TI
ratio of the LD50 to the ED50 in animal studies

Toxic effect
Undesirable drug effect that implies drug poisoning; can be very harmful or life threatening

Trade name
Patented proprietary name of a drug sold by a specific drug manufacturer; also referred to as the brand name

Pharmacodynamics
Study of the action of drugs on living tissues

Pharmacokinetics
Study of the process of drug absorption, distribution, metabolism and excretion

Pharmacotherapeutics
Study of the use of drugs in treating disease

Pharmacy
Science of preparing and dispensing medicines

Posology
Study of the amount of drug that is required to produce therapeutic effects

Toxicology
Study of harmful effects of drugs on living tissue

Schedule I Drugs
Drugs with high abuse for potential and no accepted medical use; EXAMPLES: Heroin, hallucinogens, and marijuana

Schedule II Drugs
Drugs with high abuse potential and accepted medical use; EXAMPLES: Narcotics (morphine/pure codeine), cocaine, amphetamines, short-acting barbiturates, nabilone, no refills without a new written prescription from the physician

Schedule III Drugs
Drugs with moderate abuse potential and accepted medical use; EXAMPLES: Moderate- and intermediate-acting barbiturates, dronabinol, anabolic steroids, preparations containing codeine plus another drug, prescription required, may be refilled 5 times in 6 months when authorized

Schedule IV Drugs
Drugs with low abuse potential and accepted medical use:

Schedule V Drugs
Drugs with limited abuse potential and accepted medical use

Bioavailability
Percentage of the drug dosage that is absorbed

Drug absorption
Entrance of a drug into the bloodstream from its site of administration

Drug addiction
Condition of drug abuse and drug dependence that is characterized by compulsive drug behavior

Drug dependence
Condition

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