Pharmacology Clear & Simple Ch 4

OSHA stands for:
Occupational Safety and Health Administration

FDA stands for:
Food and Drug Administration

DEA stands for:
Drug Enforcement Agency

DEA decides
which drugs are controlled and assigns drugs a schedule or category

Schedule I Drugs: examples
Heroin, LSD, methaqualone

Schedule II Drugs: examples
Morphine, PCP, cocaine, methadone, methamphetamine, Ritalin

Schedule III Drugs: examples
Anabolic steroids, codeine, hydrocodone, some barbiturates

Schedule IV Drugs: examples
Darvon, Valium, Xanax

Schedule V Drugs: examples
Cough medicines with codeine

Schedule I Drugs: abuse level
High abuse level, no medically acceptable use

Schedule II Drugs: abuse level
High abuse level, acceptable medical use, severe dependence risk

Schedule III Drugs: abuse level
Lower abuse potential, acceptable medical use, moderate to low dependence risk

Schedule IV Drugs: abuse level
Low abuse potential, acceptable medical use, limited dependence risk

Schedule V Drugs: abuse level
Lower abuse potential than Schedule IV, acceptable medical use, limited physical or psych dependence

OSHA is a branch of what govt dept:
Dept of Labor

DEA purpose:
enforcement of Controlled Substances Act, public safety

all approved drugs must be proven ___ and ____ before they can be marketed
safe and effective

common side effects
headache, nausea, vomiting, diarrhea

adverse reaction
a side effect that can cause severe harm or death (like airway swelling)

adverse reactions are reported to:
FDA’s MedWatch

placebo
inactive (inert)substance that is sometimes given to participants in clinical trials to compare it with an active substance

chemical name
mix of chemicals for a drug

after a drug passes phase III of clinical trials, it gets a ____ or ____
brand or trade name

Restoril purpose:
help patients sleep

Aleve purpose:
helps relieve pain

-caine
local anesthetics

-cillin
antibiotics

-dine
antiulcer agents

-done
opioid analgesics

-ide
oral hypoglycemics

-iam
antianxiety agents

-micin
antibiotics

-mide
diuretics

-mycin
antibiotics

-nium
neuromuscular blocking agents

-olol
beta blockers (CV)

-oxacin
antibiotics

-pam
antianxiety agents

-pril
ACE inhibitors

-sone
steroids

-statin
antilipemics

-vir
antivirals

-zide
diuretics

ETOH
alcohol

signs of substance abuse
tremors, poor judgment, slurred speech

habituated
psychologically tolerant of the drug and need an increased amount to achieve desired effect

anabolic steroids can cause:
hormone system disruptions, musculoskeletal system effects, infections, CV diseases, liver & skin dysfunction, behavioral effects

substance abuse physical signs:
sleep habits change, weight change, excessive sweating or tremors, poor coordination, needle marks, jaundice, dilated or constricted pupils

True or False: The DEA approves drugs for dispensing in the US.
True

True or False: Schedule II drugs are highly addictive.
True

True or False: OHSA is part of the Department of Health and Human Services.
False, Dept. of Labor

True or False: MedWatch is a way of reporting adverse reactions.
True

True or False: The DEA is part of the Department of Justice.
True

True or False: Clinical trials in drug development have two phases.
False, they have 4

True or False: Phase IV clinical trials happen after the drug is released to the public.
True

True or False: In a double-blind clinical trial, neither patients nor clinicians know who is receiving a drug or a placebo.
True

True or False: Generic drugs are trademark protected
False, brand or trade name drugs are protected

True or False:The drug suffix -cillin is closely associated with antibiotics.
True

The government department that enforces the Controlled Substances Act: (A)DEA (B)DOJ (C)FDA (D)DHHS (E) OSHA
(A) DEA

During the first 3 phases of clinical trials, a drug is known as: (A)Experimental new drug (B)Investigational new drug (C) Orphan drug (D)Generic drug (E) Chemical Drug
(B) Investigational new drug

Once a drug clears the 1st 3 phases of clinical trials, it’s given a __ name: (A)Generic (B)Trade (C) Brand (D)Chemical (E) B or C
(E) B or C

The most addictive schedule of drugs, with no accepted medical use, is __ drugs: (A) Schedule I (B)Schedule II (C) Schedule III (D) Schedule IV (E) Schedule V
(A) Schedule I

An example of a Schedule II drug is: (A)Heroin (B)Valium (C)Tylenol with codeine (D)Cocaine
(D) Cocaine

A damaged controlled substance should be disposed by: (A) Flushing down toilet (B)Throwing it in garbage (C)Destroying it beyond any possible use in presence of a witness (D)None of the Above
(C)Destroying it beyond any possible use in presence of a witness

What schedule includes anabolic steroids? (A)Schedule 1 (B)Schedule II (C) Schedule III (D) Schedule IV (E)Schedule V
(C)Schedule III

Symptoms of substance abuse include: (A)Tremors (B)Poor judgment (C)slurred speech (D)Change in behavior (E) All above
(E) all above

OSHA mandates that employers: (A)provide yearly safety training to employees (B)Provide protective supplies to employees (C) Report all occupational injuries (D)All above
(D) All above

The Orphan Drug Act: (A)Facilitates the development of drugs for rare diseases (B)Facilitates the development of drugs for children (C)Facilitates the development of drugs for almost eradicated diseases (D)None of the above
(A)Facilitates the development of drugs for rare diseases

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