Pharmacology chapter 15 Analgesic, antipyretic, and anti-inflammatory drugs

Acute
A) Characterized by sharpness or severity (acute pain; an acute infection).
B) having a sudden onset, sharp rise, and short course (an acute disease; an acute inflammation).

Analgesic
Insensibility to pain without loss of consciousness.

Antipyretics
Drugs that reduce elevated body temperature (fever) to normal levels.

Bradykinin
A polypeptide that mediates inflammation, increases vasodilation, and contracts smooth muscle.

Chronic
Lasting a long time or marked by frequent recurrence.

Cyclooxygenase
The name for a group of enzymes required to produce prostaglandins from arachidonic acid.

Endogenous
Caused by factors within the body or mind or arising from internal structural or functional causes (endogenous malnutrition or endogenous psychic depression); relating to or produced by metabolic synthesis in the body.

Endorphins
Any group of endogenous peptides (such as enkephalin and dynorphin) found especially in the brain that bind chiefly to opiate receptors and produce some of the same pharmacologic effects (such as pain relief) as do opiates.

Enkephalins
Peptides with opiate and analgesic activity that occur naturally in the brain and have a marked affinity for opiate receptors.

Narcotic
A medication that induces sleep or stupor and alters mood and behavior.

Neurotransmitters
Certain chemical substances, concentrated in various parts of the central nervous system, that are released by neurons and allow communication from one nerve cell to another.

Opiates
A drug (such as morphine, heroin, and codeine) containing or derived from opium and tending to induce sleep and to alleviate pain.

Opioid
Possessing some properties characteristic of opiate narcotics but not derived from opium.

Prostaglandins
Hormone like substances that control blood pressure, contract smooth muscle, and modulate inflammation.

NSAID
Nonsteroidal anti-inflammatory drug

The mechanisms actions of non-steroidal anti-inflammatory drugs (NSAIDs) To summarise, non-steroidal anti-inflammatory drugs are drugs which have anti-inflammatory, analgesic and antipyretic properties due to their mechanism and enzymes involved COX-1 and COX-2. However as well as being beneficial NSAIDs have …

Overview Inflammation is a normal, protective response to tissue injury caused by physical trauma, noxious chemicals, or microbiologic agents. Inflammation is the body’s effort to inactivate or destroy invading organisms, remove irritants, and set the stage for tissue repair. When …

analgesic compounds with pain-blocking properties, capable of producing analgesia anti-inflammatory agents drugs that block the effects of the inflammatory response WE WILL WRITE A CUSTOM ESSAY SAMPLE ON ANY TOPIC SPECIFICALLY FOR YOU FOR ONLY $13.90/PAGE Write my sample antipyretic …

NSAIDs action 1. NSAIDs inhibit prostaglandins 2. Cox-2 inhibitors block the enzyme responsible for inflammation without blocking the Cox-1 enzyme 3. ASA has anti-platelet activity NSAIDs indications 1. Pain, fever, arthritis, dysmenorrhea 2. ASA: transien ischemic attacks (TIAs), prophylaxis of …

Cardinal signs of inflammation erythema, edema, heat, pain, loss of function Inflammation is a response to tissue injury and infection WE WILL WRITE A CUSTOM ESSAY SAMPLE ON ANY TOPIC SPECIFICALLY FOR YOU FOR ONLY $13.90/PAGE Write my sample Infection …

adjuvant a drug added to a prescription to hasten or enhance the action of a principal ingredient Analgesics medications that alleviate pain WE WILL WRITE A CUSTOM ESSAY SAMPLE ON ANY TOPIC SPECIFICALLY FOR YOU FOR ONLY $13.90/PAGE Write my …

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