NP Pharmacology

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Thiazolidinediones (TZDs)
Rosiglitazone or pioglitazone. Black box warning: caise or exacerbate CHF. Don’t use if NYHA Class III or IV heart failure. Stop pioglitazone (Actos) if c/o dyspnea, weight gain, cough.

Atypical antipsychotics: Risperidone (Risperdal), olanzapine (Zyprexa), quietipine (Seroquel)
High risk of weight gain, metabolic syndrome, type II diabetes. Monitor weight every 3 months. BBW: higher mortality in elderly patients. Monitor: TSH, lipids, weight/body mass index.

Bisphosphonates: Alendronate (Fosamax), risedronate (Actonel)
Jaw pain (jaw necrosis). Chest pain, difficulty swallowing, burning mid-back (perforation). Take alone upon awakening with 8oz glass water (NOT juice) before breakfast, first thing in the morning. Do not lie down for 30 minutes afterwards. Do not mix with other drugs).

Statins drugs
Do not mix with grapefruit juice. Drug-induced hepatitis or rhadomyolysis higher if mixed with azole antifungals. High dose Zocor (80mg) has highest risk of rhabdomyolysis (muscle pain/tenderness). CK (creatine kinase) level goes up).

Lincosamides – Clindamycin (Cleocin)
Higher risk of Clostrodium Difficile-associated diarrhea (CDAD). Treated with Metronidazole (Flagyl) PO TID x10-14 days. Probiotics daily BID x a few weeks.

We use cookies to give you the best experience possible. By continuing we’ll assume you’re on board with our cookie policy Byetta Inject Subq Expect Peak 2hr Use the drug as a supplement Pioglitazone (Actos Weight Gain WE WILL WRITE …

We use cookies to give you the best experience possible. By continuing we’ll assume you’re on board with our cookie policy When talking with a patient who is about to begin exenatide (Byetta) therapy to treat type 2 diabetes mellitus, …

We use cookies to give you the best experience possible. By continuing we’ll assume you’re on board with our cookie policy Infants are at risk for drug toxicity due to which of the following? Decreased liver enzymes, reduced kidney perfusion, …

We use cookies to give you the best experience possible. By continuing we’ll assume you’re on board with our cookie policy Lipoprotein the combination of triglyceride or cholesterol with apolipoprotein Very low density lipoprotein produced by the liver, transports endogenous …

We use cookies to give you the best experience possible. By continuing we’ll assume you’re on board with our cookie policy A health care professional obtaining a patient’s health history discovers that the patient is taking loratadine (Claritin), an over …

We use cookies to give you the best experience possible. By continuing we’ll assume you’re on board with our cookie policy Three rapid acting insulin drugs Lispro Aspart Glulisine “Rapid drugs don’t LAG” “Rapid drugs don’t LAG” Mnemonic to remember …

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