NP Pharmacology

Thiazolidinediones (TZDs)
Rosiglitazone or pioglitazone. Black box warning: caise or exacerbate CHF. Don’t use if NYHA Class III or IV heart failure. Stop pioglitazone (Actos) if c/o dyspnea, weight gain, cough.

Atypical antipsychotics: Risperidone (Risperdal), olanzapine (Zyprexa), quietipine (Seroquel)
High risk of weight gain, metabolic syndrome, type II diabetes. Monitor weight every 3 months. BBW: higher mortality in elderly patients. Monitor: TSH, lipids, weight/body mass index.

Bisphosphonates: Alendronate (Fosamax), risedronate (Actonel)
Jaw pain (jaw necrosis). Chest pain, difficulty swallowing, burning mid-back (perforation). Take alone upon awakening with 8oz glass water (NOT juice) before breakfast, first thing in the morning. Do not lie down for 30 minutes afterwards. Do not mix with other drugs).

Statins drugs
Do not mix with grapefruit juice. Drug-induced hepatitis or rhadomyolysis higher if mixed with azole antifungals. High dose Zocor (80mg) has highest risk of rhabdomyolysis (muscle pain/tenderness). CK (creatine kinase) level goes up).

Lincosamides – Clindamycin (Cleocin)
Higher risk of Clostrodium Difficile-associated diarrhea (CDAD). Treated with Metronidazole (Flagyl) PO TID x10-14 days. Probiotics daily BID x a few weeks.

Byetta Inject Subq Expect Peak 2hr Use the drug as a supplement Pioglitazone (Actos Weight Gain WE WILL WRITE A CUSTOM ESSAY SAMPLE ON ANY TOPIC SPECIFICALLY FOR YOU FOR ONLY $13.90/PAGE Write my sample Insulin Glargine – precautions because …

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A health care professional obtaining a patient’s health history discovers that the patient is taking loratadine (Claritin), an over the counter drug. Which of the following information about over the counter drugs is correct? (select all that apply) They do …

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