Mannitol (Osmitrol, Resectisol)

Mannitol (Osmitrol, Resectisol)
Pharmacological Class:
Osmotic Diuretic

Mannitol (Osmitrol, Resectisol)
Therapeutic Class:
Pregnancy Category C drug.

Mannitol (Osmitrol, Resectisol)
Used in acute renal failure, high intraocular or intracranial pressure, edema, and drug intoxication (to induce diuresis). Mannitol works along the entire nephron and is non-absorbable. It inhibits reabsorption of H2O and lytes. Take away- mannitol is pulling fluids from the interstitial spaces into the vasculature.

Mannitol (Osmitrol, Resectisol)
hypokalemia increases risk for dig toxicity

Mannitol (Osmitrol, Resectisol)
known allergy, severe pulmonary edema (use loop diuretics instead), anuria, severe dehydration, pulmonary congestion, active intracranial bleeding. Use caution in clients who have HF.

Mannitol (Osmitrol, Resectisol)
Administration Considerations:
Mannitol may crystallize at low temperatures so it needs to be stored in a warmer. Because of this, it is always administered IV through a filter. Visually inspect mannitol container for precipitants prior to administration.

Mannitol (Osmitrol, Resectisol)
Immediately terminate treatment if severe cardiac or renal impairment develop after initiation of therapy.

Mannitol (Osmitrol, Resectisol)
Adverse/Side Effects:
Convulsions, thrombophlebitis, pulmonary congestion or edema, HF,, kidney failure, fluid and lyte imbalances, increased GFR and renal plasma flow, h/a, chest pain, tachycardia, blurred vision, chills, fever

Mannitol (Osmitrol, Resectisol)
Nursing Considerations:
Administer by continuous IV infusion. Use a filter needle when drawing from the vial and a filter in the IV tubing to prevent administration of microscopic crystals. Monitor daily weight, I&O, serum lytes & for signs of dehydration, acute kidney injury, and edema.

acetazolamide (Diamox) – Indications Carbonic anhydrase inhibitor. open-angle glaucoma, pre-op treatment of closed-angle glaucoma, seizure disorder, edema, high-altitude sickness. acetazolamide (Diamox) – MOA Inhibits carbonic anhydrase in kidneydecreases water reabsorption, increases Na+ & K+ excretion. Decreases aqueous humor production. WE …

Mannitol (Osmitrol) Osmotic Diuretic How Mannitol (Osmitrol) works: Affects/Reduces ICP in two ways: 1. Plasma Expansion 2. Osmotic Effect WE WILL WRITE A CUSTOM ESSAY SAMPLE ON ANY TOPIC SPECIFICALLY FOR YOU FOR ONLY $13.90/PAGE Write my sample Plasma Expansion …

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Diuretic Drugs –Drugs that accelerate the rate of urine formation –Result in the removal of sodium and water –Used in the treatment of hypertension, heart failure, and renal failure Sodium –In the nephron, where sodium goes, water follows -60% to …

List the major pathologic/structure changes. a. Interstitial edema b. Alveolar flooding c. Increased surface tension d. Alveolar shrinkage and atelectasis e. Frothy white or pink secretions What are the common causes of cardiogenic pulmonary edema? a. Left sided heart falure …

Diuretics purpose to decrease body fluids Water follows sodium Na reabsorption blocked so less H20 reabsorbed Inc. glomerular filtration rate (GFR) Increase Na excretion rate = inc. H20 excretion Thiazide Diuretics Hydrochlorodiazide (HCTZ) or Chlorothiazide (Diuril) Sulfonamide derivatives (antibiotic) WE …

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