1. The company and the brand 2. The Medihoney™ products 3. How to use Medihoney™ wound products 4. Potential side effects 5. General questions 6. Medihoney™ products for use on unbroken skin 7. References 8. Product range 8. 1 Medihoney™ Antibacterial Medical Honey™ 8. 2 Medihoney™ Antibacterial Wound Gel™ 8. 3 Medihoney™ Derma Cream 8. 4 Medihoney™ Barrier Cream [pic]
Comvita NZ Limited Wilson Road South Private Bag 1 Te Puke 3153 0800 504 959 This document, or part of, may not be reproduced or transmitted in any form without the prior permission of Comvita 1. 0 The company and the brand Tell me about Comvita®.
Comvita® is a natural products company based in New Zealand. As a company Comvita® aims to change perceptions of natural health by applying science and innovation. Their New Zealand origin and culture drives new thinking. The company is passionate about the quality and effectiveness of the products that they make.
They believe that nature holds the key to a better quality of life, but still care for the future of people and nature. In this regard they apply integrity and sustainable principles in everything that they do. Comvita® is a global leader in medical honey and the world’s largest supplier of honey from Leptospermum sp.
Tell me about Comvita® Medihoney™ Medihoney™ is the brand name for Comvita®’s medical honey based product range. Each of the products contains ‘Medihoney™ antibacterial honey’. This is a standardised medical honey from predominantly Leptospermum species (Manuka is one of the Leptospermum species).
The combination of honeys has been put together to maximise honey’s potential to heal. We know that Manuka (and other Leptospermum varieties) has exceptional antibacterial properties due to the UMF® activity; our ‘blend’ contains UMF™ Manuka honey and offers the very best of honey’s wound healing actions.
I thought Manuka honey was the best honey for wounds. Manuka is one of the plants in the Leptospermum species identified to have exceptional antibacterial properties. It is the best known variety of the Leptospermum species and is the only one found in New Zealand (all the other Leptospermum varieties can be found in Australia and may number up to 80). Medihoney™ products contain a spectrum of Leptospermum honeys (including Manuka) to ensure that the end-products maximise honey’s potential to heal.
What has prompted the resurgence of honey products for wounds? Historically, honey has been used for healing purposes for over 2000 years and was also used to treat wounds in both World Wars.
The discovery of antibiotics led to a decline in its use. With the increase in the numbers of emerging strains of bacteria resistant to antibiotics, honey products are once again gaining acceptance. By choosing the Medihoney™ brand you are using tried and tested, quality, standardised products manufactured under strict pharmaceutical grade control.
Medihoney™ antibacterial honey has demonstrated the ability to inhibit the growth of even the most multi-resistant strains of bacteria1; there is no known bacterial resistance to its action. What’s the difference between Medihoney™ products and other honey products available for application to wounds? 1) Raw product traceability and quality – Medihoney™ products only use honey supplied by formally accredited beekeepers that have to meet stringent quality control measures to ensure the honey supplied is as active and pure as possible.
2) Comvita® managed supply process – Comvita® has their own bee hives and has secure relationships with many beekeepers. In order to cope with predicted increased requirements for Medihoney™ products, they are replanting large areas of unprofitable land with Leptospermum species, in a project that will assist with carbon neutrality. 3) Not all honeys are equal when it comes to their wound healing and antibacterial effects.
Recently advanced biomedical research has identified specific plants that produce honey with exceptional antibacterial properties i.e. Leptospermum sp. , of which Manuka is the best recognised. This property is extremely stable and can be referred to as ‘non-peroxide activity’. The specific honey ‘blend’ used in the Medihoney™ antibacterial honey has been developed to maximize honey’s potential to heal. 4)
There are more published research articles on the Medihoney™ products than any other honey brand, giving end-users confidence in the products. Medihoney™ dressings are currently used by hospitals worldwide and an ongoing research programme is in place. 2. 0 The Medihoney™ Products What are the Medihoney™ products?
Currently the Medihoney™ range includes an Antibacterial Medical HoneyTM and an Antibacterial Wound Gel™, which both come in a tube. Either of these is appropriate for application to an open wound. The range also includes a Derma Cream and a Barrier Cream, which both contain a range of natural ingredients including Medihoney™ antibacterial honey.
The Derma Cream is appropriate for dry skin conditions, while the Barrier cream will protect skin in ‘wet’ areas, such as under nappies. Medihoney™ wound products Tell me more about each of these wound products? Medihoney™ Antibacterial Wound Gel™ contains 80% Medihoney™ antibacterial honey combined with 20% waxes. The waxes change the viscosity of the honey to provide easier application and better handling (i. e. it is less runny).
This product is however not suitable for cavity wounds, fistulas or sinuses as the waxes may be difficult to clean out from deep in the tissues. Medihoney™ Antibacterial Medical Honey™ contains 100% honey and therefore is suitable for such cavities. It is slightly runnier than the Antibacterial Wound Gel™.
Both these products are equally effective; product choice is at the discretion of the user (except in the case of the deep cavities mentioned above). Both products will require the use of secondary dressings appropriate to the degree of exudate. An absorbent dressing will be required for more heavily exudating wounds, while a semi-permeable film might be appropriate for a dry wound.
The choice of the secondary dressing will also be influenced by the position of the wound and the fragility of the patient’s skin. How do Medihoney™ wound products help a wound to heal? Medihoney™ wound products act to clean, protect and heal a wound.
Clean: Medihoney™ products help reduce the inflammatory response by assisting in cleaning the wound of bacteria through its osmotic action 2,3,4,5,6,7,8,9. They assist in the removal of slough and necrotic tissue and rapidly remove malodour. Protect: Medihoney ™ wound products provide an effective antibacterial barrier that inhibits bacterial growth including antibiotic resistant strains 1,6,8,10,11,12,13-22.
Heal: Medihoney™ wound products provide a moist wound healing environment. Research shows that a moist wound environment supports fibroblasts in building the small blood vessels and connective tissue in the granulation process (i.
e. the process that repairs the wound deficit). Chronic non-healing wounds tend to have an elevated pH 23,24,25. The use of Medihoney™ wound products can significantly reduce surface wound pH26. As the wound products are non-adherent they reduce pain and trauma during dressing changes. What creates the antibacterial barrier of the Medihoney™ wound products? 1) Medihoney™ antibacterial honey has a high sugar and low water content. This creates an osmotic action which assists the removal of bacteria from the wound bed; bacteria also have insufficient water to support their growth.
2) The natural acidity of the honey (pH 3. 2-4. 5) also inhibits bacterial growth. 3) Internal buffering systems help to maintain honey’s acidic pH despite dilution by wound exudate. 4) Leptospermum honey has special antibacterial properties over and above those presented. This type of activity has only ever been found in Leptospermum honey.
In Manuka honey this has been termed ‘Unique Manuka Factor’ or UMF™ for short. Other Leptospermum varieties can also exhibit this antibacterial property – it is measured by the same test method and is often called ‘phenol equivalence’ or PE value for short.
UMF™ and PE are both a numerical measure of the same thing. 3. 0 How to use the Medihoney™ wound products What types of wound can benefit from the application of Medihoney™ wound products? Medihoney™ wound products are indicated for all types of wounds whether they be simple grazes and cuts, burns, ulcers (leg, foot, pressure), surgical wounds or graft sites. They are appropriate for sloughy wounds and malodorous wounds at all sites and all stages of healing. How should the Medihoney™ wound products be applied to a wound?
Medihoney™ Antibacterial Wound Gel™ and Antibacterial Medical Honey™ should be applied directly to the open wound at a height of 3mm. How often do I need to change the Medihoney™ wound products? The frequency of dressing change is dependent on the amount of exudate (or ooze) coming from the wound.
Dependent on the amount of exudate, wounds may require daily dressing changes, while non-exudating, dry wounds may be left undisturbed for up to 7 days. Are Medihoney™ wound products going to stick to the wound bed? If applied properly, in adequate amounts, dressings covering the wound should not adhere.
Generally, if adhesion does occur, either too little of the Medihoney™ wound product has been used or the dressing was kept on the wound for too long. How do I remove Medihoney™ wound products? Medihoney™ wound products will wash off the wound using standard measures, such as saline or water. Do Medihoney™ wound products cause maceration of the skin surrounding the wound? Medihoney™ wound products will naturally, osmotically draw fluid away from the wound into the dressing, which should avoid maceration.
Skin may macerate if the choice of secondary dressing is inappropriate i. e. it does not absorb sufficient exudate, or if the dressings are not changed frequently enough. If the wound is heavily exudating the skin surrounding the wound could be protected with Medihoney™ Barrier Cream, as an extra precautionary measure. However, this is not a substitute for regular dressing changes in the heavily exudating wound. Can Medihoney™ wound products stain the skin?
Medihoney™ wound products can leave a brown stain on the skin surrounding the margin of a wound. It is not permanent and will disappear once you stop using it. Can you put too much honey on a wound?
Increasing the application of the Medihoney™ wound product over that recommended will not be harmful to the wound just so long as the dressings are changed in accordance with wound exudate levels. However, it is unlikely to provide ‘better’ healing conditions (optimum healing occurs at the recommended rate) and is likely to be difficult to hold on the wound and therefore may be messy.
Can Medihoney™ products be diluted or mixed with other wound materials before application to a wound? We would not advise such practice. Medihoney™ wound products have been shown to protect, clean and heal wounds in the context of the branded products.
Medihoney™ wound products work because of their osmotic, acidic, antibacterial barrier and moist wound healing environment properties. Dilution of the Medihoney™ wound product would undoubtedly alter these characteristics. 4. 0 Potential Side Effects Why do Medihoney™ wound products sometimes cause pain? It has been recognised through clinical practice that some patients experience pain at their wound site, often described as stinging, on application.
This often resolves spontaneously after a period of a few minutes. It has been noted rarely the pain is intolerable and in such cases the Medihoney™ wound product will need to be removed.
It is important to note that pain is not an indication of wound damage – if the pain can be tolerated wounds still continue to heal. While we are not certain of the aetiology of the pain it is thought to be associated with the natural acidity of Medihoney™ products and their osmotic, drawing effect. Is there anything you can do about the pain?
Experience has shown us that, if using the Medihoney™ Antibacterial Medical Honey™, application of the Antibacterial Wound Gel™ instead might solve the problem. It should also be noted that as wounds heal any associated pain usually settles.
If the pain is intolerable and cannot be managed using the above measures, the Medihoney™ wound product should be washed off. Pain on application at one particular site should not rule out Medihoney™ wound products as the dressing of choice for future wounds, or even the same wound at a different stage of its healing. Are there any contraindications?
Those specifically allergic to honey should avoid using honey dressings. Those allergic to bee stings should be able to use the Medihoney™ wound products; the components of bee stings which create the allergy do not occur in honey. 5.
0 General Questions Can I use organic honey or supermarket honey on my wound? The quality criteria used for products taken internally and those applied to open wounds is quite different. Medihoney™ wound products meet much stricter quality control measures and have also been tested to ensure they meet specific levels of antibacterial activity.
Medihoney™ wound products have also been sterilised to ensure clostridium spores do not enter the body through the open wounds, thus potentially leading to botulism. | |Supermarket / Organic |Medihoney™ antibacterial honey | |Microbial count.