Essentials of Pharmacology for Health Professionals 7th Edition Chapter 3

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Drug
a chemical substance that when absorbed into the body that changes their normal body function

Chemoinformatics
is the application of computer technology, statistics, and mathematics to study info. about the structure, properties, and activities of molecules.

Genetic engineering
The alteration of genes in a lab setting

Systemic effect
reaches widespread areas of the body

Local effect
is limited to one area of the body

Drug Process
Absorption, Distribution, Metabolism, and Excretion

Absorption
Passage of substance through a membrane to the blood stream

Distribution
Moving from the bloodstream into the tissues and fluids of the body

Metabolism
physical and chemical alterations that occur in the body

Excretion
Elimination of waste products from the body.

Prodrugs
drugs that are activated by the liver

Therapeutic range
The dose or dosage of a drug that produces the desired effect with minimal or no signs of toxicity.

Synergism
When antibiotics work together

Potentiation
when one drug opposes the other and increases the activity of the other drug to produce an effect

Antagonism
Drugs oppose each other with no effect

Pharmacogenomics
examines how genes may explain a drug’s effectiveness and toxicity

Routes of administration
Enteral or GI tract routes and Parenteral routes

Teratogenic effect
drugs that cause abnormal fetal development when given to pregnant women

Idiosyncratic reaction
an unexpected reaction to a drug

Paradoxical reaction
causing an effect opposite of the intended effect

Anaphylactic reaction
severe,possibly fatal allergic response

Tolerance
Decreased response to a drug that develops after repeated doses are given

Dependence
The situation that occurs when the drug becomes part of the body’s functioning and produces withdrawal symptoms when the drug is discontinued

We use cookies to give you the best experience possible. By continuing we’ll assume you’re on board with our cookie policy Process by which the body takes in or receives a drug Absorption Action by which a drug is released …

We use cookies to give you the best experience possible. By continuing we’ll assume you’re on board with our cookie policy Trade name Also known as the drug’s brand name Official name A drug name given by the Food and …

We use cookies to give you the best experience possible. By continuing we’ll assume you’re on board with our cookie policy What is pharmacology? The study of drugs What is a drug? Also referred to as a ligand. A chemical …

We use cookies to give you the best experience possible. By continuing we’ll assume you’re on board with our cookie policy What is pharmacology? study of drugs What is a dose? exact amount of drug that is administered in order …

We use cookies to give you the best experience possible. By continuing we’ll assume you’re on board with our cookie policy angina pectoris spasmlike pain in the chest caused by myocardial anoxia bronchodilator drug that relaxes contractions of the smooth …

We use cookies to give you the best experience possible. By continuing we’ll assume you’re on board with our cookie policy Pharmacodynamics facts Pharmacodynamics is the science of dealing with interactions between living organisms and foreign chemicals. Each living system …

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