Diazepam (Valium) Intro to Pharmacology Drug Quiz #8

Diazepam (Valium)
Mechanism of Action 1/3
Binds to the benzodiazepan receptor and enhances the effects of GABA.

Diazepam (Valium)
Mechanism of Action 2/3
Benzodiazepines act at the level of the Limbic, Thalamic, and Hypothalmic regions of the CNS

Diazepam (Valium)
Mechanism of Action 3/3
and can produce any level of CNS depression required (sedation, skeletal muscle relaxation, and anticonvulsant activity)

Diazepam (Valium)
Indications 1/4
Anxiety

Diazepam (Valium)
Indications 2/4
Skeletal muscle relaxation

Diazepam (Valium)
Indications 3/4
Alcohol withdrawal

Diazepam (Valium)
Indication 4/4
Seizures

Diazepam (Valium)
Contraindications 1/5
Children younger than 6 yrs old

Diazepam (Valium)
Contraindications 2/5
Acute angle glaucoma

Diazepam (Valium)
Contraindications 3/5
CNS depression

Diazepam (Valium)
Contraindications 4/5
Alcohol Intoxication

Diazepam (Valium)
Contraindications 5/5
Known Sensitivity

Diazepam (Valium)
Dosage and Routes (Adult Anxiety Mod and Sev) 1/2
Moderate
2-5 mg slow IV,IM
Severe
5-10 mg slow IV,IM (no faster than 5 mgmin

Diazepam (Valium)
Dosage and Routes (Seizures) 2/2
5-10 mg slow Iv,IO every 10-15 min; Max dose 30 mg

Lorazepam (Ativan) Mechanism of Action 1/2 Binds to the benzodiazepan receptor and enhances the effects of the brain chemical GABA, an inhibitory transmitter Lorazepam (Ativan) Mechanism of Action 2/2 And may result in a state of sedation, hypnosis, skeletal muscle …

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