Alkylating antineoplastic agent

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A nurse has to administer 0.06 ml/kg of hep B immune globulin IM to a pt. the total body weight of the pt is 50 kg. How many ml of the drug should be administered to the pt. 3 ml.A nurse is required to administer a varicella vaccine to a female pt planning to start a family. How long after the vaccination should the nurse instructs the pt to wait before getting pregnant?
12 weeks
A child is brought by his parents to the HCF for MMR vaccination. On taking the medical hx, the nurse understands that the child had received an antivenin injection for snakebite 2 days before. Which of the following is the most appropriate time period for administration of live vaccines to the child?

After 6 to 12 weeks
A child who is recovering from a chickenpox infection is given aspirin for his fever. Which of the following conditions develop following the simultaneous administration of salicylates and the varicella vaccine?

Reye’s syndrome
When educating a group of nursing students on immunologic agents, the nurse explains about a particular kind of immunity that develops by injecting ready-made antibodies found in the serum of immune individuals or animals. Which of the following kinds of immunity is the nurse referring to?

Passive immunity
A pt with a hx of chronic cough is suspected of having pulmonary TB. Which of the following vaccinations is used to prevent the condition?
BCG vaccine
A forest ranger arrives at a community clinic for prophylactic vaccination. Which of the following vaccines would be most important to be administered to the ranger?
Rabies vaccine
A nurse is caring for a pt who has been bitten by a coral snake. Which of the
following agents is to be administered to the pt in this condition?
Antivenin

A nurse is educating a group of nursing students about the immediate reactions after administering antivenins. Within which of the following time periods will the immediate reaction be seen if the pt is sensitive to the antivenin?

30 minutes
When educating a group of nursing students on immunologic agents, the nurse refers to a substance that is attenuated (or weakened) but still capable of stimulating the formation of antitoxins. Which of the following is the nurse referring to?

Toxoids

Chapter 51
A pt visits the HCF for info on cancer. The pt asks the nurse if regular consumption of green tea can cause harm. Which of the following should the nurse inform the pt as possible effects of green tea?

Insomnia
A nurse is caring for a pt who is prescribed velban, a vina alkaloid. The pt wants to know the action of the drug on the cell cycle. Which of the following should the nurse inform the pt?
Interferes with amino acid production in the S phase
A pt has been prescribed tx with antineoplastic drugs, which have a depressing effect on the bone marrow. What pre-administration assessment should the nurse perform for this pt with respect to the depressing effect of the bone marrow?

Complete blood count
A nurse is caring for a pt being treated with antineoplastic drugs. The pt is at risk for thrombocytopenia due to bone marrow suppression. What should the nurse monitor for in this pt?
Bloody urine
A pt is to start with chemotherapy. The pt is worried about going bald in the course of the tx. How can the nurse assist the pt in being comfortable with his or her body image?
Suggest the use of a wig or cap
A nurse is caring for a pt who is at risk or erythema during antineoplastic drug therapy. What should the nurse suggest to this pt?
Wear loose protective clothing
A pt has been dx with cancer. The physician prescribes antineoplastic drug therapy to the pt. how should the nurse explain the use of antineoplastic drugs?
Delays spread of cancer to other sites
A pt has been prescribed melphalan, an alkylating agent, for the tx of ovarian tumor. The pt wants to know the action of the drug in treating the tumor. Which of the following should the nurse inform the pt

Changes the cell to a more alkaline environment
A nurse is caring for pt undergoing tx with plant alkaloids for cancer. The pts is also administered warfarin for a hz of atrial fibrillation. Which of the following is an interactive effect of the 2 drugs which the nurse should monitor the pt for?

Increased risk of prolonged bleeding
A pt undergoing antineoplastic drug therapy is administered an alkylating drug. The pt is also administering an aminoglycoside as an anti-infective agent. Which of the following interactions of the alkylating drug with the anmioglycoside should the nurse assess the pt for?

Increased risk for nephrotoxicity

Chapter 52
Prior to administerinig a drug used to treat anemia, the nurse should assess a client’s vitals, client’s ability to carry out activities of daily living, general appearance, and for the presence of which of the following other general symptoms?

Sore tongue, fatigue, headache, pallor, SOB
A pt with iron-deficiency anemia is prescribed iron supplements. Which of the following adverse GI reactions should the nurse closely monitor for in the pt?
Darker stools
A pt has been administered iron preparation for treating iron-deficiency anemia. The pt has informed the nurse that she has also been taking ascorbic acid. Which of the following conditions should the nurse monitor for as a result of the interaction between iron and ascorbic acid?

Increased absorption of iron
A pt with megaloblastic anemia is to be administered leucovorin. For which of the following conditions is leucovorin contraindicated in this pt?
Pernicious anemia.
A nurse is caring for a pt with iron-deficieency anemia. What information should a nurse provide to the pt receiving oral iron supplements?
Color of stools will become darker
A pt who was treated for anemia is being discharged. The pt has been instructed to continue with epoetin alfa for a wk, which of the following points should the nurse include in the teaching plan to educate the pt about the therapy when caring for the pt on an outpatient basis?

Report to the PHCP on experiencing signs of joint pain
A nurse is caring for a pt with hypertension who is prescribed epoetin for anemia. Which of the following interventions should the nurse perform when administering epoetin to this pt?
Note the hematocrit value before each dose during therapy
A pt is prescribed vit B12 for his pernicious anemia following gastric bypass surgery. Which of the following adverse reactions should the nurse closely monitor for in this pt?
Pulmonary edema.
A nurse is caring for a pt experiencing constipation. What instructions should the nurse offer this pt when providing care to relieve constipation?
Consume a diet high in fiber
A nurse is caring for a pt who has been prescribed iron dextran. Which of the following information is necessary for the nurse to calculate the drug dosage?
Hemoglobin level.

Chapter 53
A nurse is caring for a patient who is prescribed benzocaine for topical anesthesia in local skin. Which of the following adverse reactions to benzocaine should the nurse monitor in the patient?
Stinging, tenderness, and sloughing
The primary health care provider has prescribed dexamethasone sodium phosphate for a patient being treated for immunologic skin. Which of the following adverse reactions to dexamethasone sodium phosphate should the nurse monitor in the patient?

Allergic contact dermatitis
Chlorhexidine gluconate is being used in a patient for preoperative skin preparation. Which of the following adverse reactions to chlorhexidine gluconate should the nurse monitor in the patient?
Deafness.
A nurse is caring for a patient who is prescribed haloprogin for the treatment of tinea manuum. Which of the following adverse reactions to haloprogin should the nurse monitor in the patient
Vesicle formation
Mupirocin is being used nasally in a patient for treating eradication of methicillin-resistant S. aureus (MRSA). Which of the following adverse reactions to nasal mupirocin should the nurse monitor in the patient?

Respiratory disorders
Azelaic acid is being used in a patient for the treatment of rosacea. Which of the following adverse reactions to azelaic acid should the nurse monitor in the patient?
Transient pruritus
The primary health care provider has prescribed benzoyl peroxide for a patient being treated for moderate acne vulgaris. Which of the following
adverse reactions to benzoyl peroxide should the nurse monitor in the patient?

Excessive drying
A nurse is caring for a patient who has been prescribed lidocaine viscous to be used for oral anesthesia for the control of pain. Which of the following instructions regarding the intake of food should the nurse give the patient?

Do not eat food for 1 hr after use
A patient has been prescribed actinex for the removal of warts. Which of the following is an adverse reaction to keratolytic drug actinex about which the nurse should inform the patient?
Flu-like syndrome.
A nurse is caring for a patient who has been prescribed collagenase by the primary health care provider. The nurse should know that in which of the following is collagenase contraindicated
In wounds in contact with major body cavities.

Chapter 54
A nurse is caring for a patient who is prescribed Coly-Mycin S Otic for bacterial infections of the external auditory canal. Which of the following instructions should be followed by the nurse administering the otic solution?

When the pt is upright, remove the solution running out of the ear with gauze A patient with open-angle (chronic) glaucoma has been prescribed brimonidine tartrate for lowering intraocular pressure (IOP). Which of the following should the nurse monitor in the patient as a local effect of brimonidine tartrate?

Foreign-body sensation
A patient with glaucoma has been prescribed carbachol. Which of the following should the nurse monitor in the patient as a systemic adverse reaction to carbachol?
Breathing difficulties.

Brinzolamide is being administered to a patient who is being treated for ocular hypertension. The nurse caring for this patient should know that which of the following is a systemic reaction to brinzolamide?

Bitter taste
A patient is being treated for inflammation of the anterior segment of the eye and has been prescribed dexamethasone phosphate. The nurse caring for the patient should know that which of the following is a local adverse reaction to dexamethasone phosphate?

Loss of visual acuity
Trifluridine is being administered to a patient who is being treated for epithelial keratitis. The nurse caring for this patient should know that which of the following is a local reaction to trifluridine?

Edema of the eyes

Chapter 55
True and False.

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