Adverse drug reaction

Example of short answer questions

1 .What is the therapeutic range of a drug?

2. Describe the term drug half life.

3. Can you describe the term concordance?

4. Describe the difference between an agonist and an antagonist drug

5. When monitoring adverse reactions yellow card reporting is used to?

Answer Q1.
The Therapeutic range is the range of drug levels within which most patients will experience significant therapeutic effect without an undesirable degree of adverse reactions. The ranges quoted should be used as a guide only because individual patients may have differences in drug distribution or transport which alter drug availability at the receptor.

Answer Q2.
The duration of action of a drug is known as its half life. This is the period of time required for the concentration or amount of drug in the body to be reduced by one-half. We usually consider the half life of a drug in relation to the amount of the drug in plasma. A drug’s plasma half-life depends on how quickly the drug is eliminated from the plasma.

Answer Q3.
a medical context refers to a patient both agreeing to and then undergoing some part of their treatment program as advised by their doctor or other healthcare worker. Most commonly it is whether a patient takes their medication, but may also apply to use of surgical appliances (e.g. compression stockings), chronic wound care, self-directed physiotherapy exercises, or attending for a course of therapy (e.g. counselling).

A patient may or may not accurately report back to their healthcare workers whether they have been compliant because of possible embarrassment, fear of being chastised or for seeming to be ungrateful for their doctor’s care.

Answer Q4. An agonist is drug that has an affinity for a receptor and once bound to that receptor causes a specific response. An antagonist is a drug which has an affinity for a receptor but does not cause a specific response.

Answer Q5. to report all suspected adverse drug reactions to new drugs and any serious reaction to all drugs.

?Describes the drug’s chemical composition and molecular structure Generic name (nonproprietary name) ?NAME GIVEN BY THE UNITED STATES ADOPTED NAMES Council Trade name (proprietary name) ?THE DRUG HAS A REGISTERED TRADEMARK; USE of the name is restricted by the drug’s …

1. A number of drugs have been used for centuries, either as remedies or in religious ceremonies. Describe how three of these drugs were used by ancient civilization and how they are used today. Include in your answer the improvements …

Indications| Complete or partial reversal of the central sedative effects of benzodiazepines. It is therefore used in anesthesia and intensive care in the following indications:Anesthesia: Termination of general anesthesia induced and maintained with benzodiazepines in in-patients. Reversal of benzodiazepine sedation …

1. Cell injury (a) Cause and mechanism: Ischemic, Toxic and Apoptosis (b) Reversible cell injury: Types, morphology, hyaline, fatty change (c) Irreversible cell injury: Types of necrosis, gangrene (d) Calcification: Dystrophic and metastatic (e) Extracellular accumulation: Amyloidosis, classification, pathogenesis, morphology …

1. Cell injury (a) Cause and mechanism: Ischemic, Toxic and Apoptosis (b) Reversible cell injury: Types, morphology, hyaline, fatty change (c) Irreversible cell injury: Types of necrosis, gangrene (d) Calcification: Dystrophic and metastatic (e) Extracellular accumulation: Amyloidosis, classification, pathogenesis, morphology …

Background: Polypharmacy is common among older people. The purpose of this study is to describe GPs’ views and beliefs on polypharmacy in order to identify the role of the GP in relation to improving prescribing behaviour. The awareness of these …

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