The likelihood that things will dissociate
The drug concentration required to produce 1/2 max occupancy of the receptor proteins
The KD will be greater, but the Bmax remains the same
The KD will be the same, but the Bmax is lower (lower max % of receptors that a given drug can bind.
The KD can either be larger or smaller, but B max remains the same
Binds to the receptor (Affinity), but doesn’t have any response (efficacy)
Concentration of drug required to produce 50% of THAT drugs maximum response